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Dataset

NG00040 - Multi-Ethnic Exome Array Study of AD, FTD, and PSP

Overview

A multi-ethnic exome array study to identify low-frequency coding variants that affect susceptibility to Alzheimer's disease, frontotemporal dementia, and progressive supranuclear palsy. Also included are variant-level and gene-level association statistics. The p-value data is available to all users, while the access to the Exome Array data would be available soon.

NIAGADS staff is collecting Genomic Data Sharing (GDS) documentation for this dataset. Until we know how the study's cohort's Institutional Review Board wants the data to be shared, the data cannot be distributed. Information about GDS is available at https://osp.od.nih.gov/scientific-sharing/genomic-data-sharing/. If you have questions about GDS, you may contact Dr. Marilyn Miller, millerm@nia.nih.gov. In the meantime, you may still submit a request for this dataset, but it will not be distributed until GDS documentation is complete.

Molecular Data Type

Disease

Submission date: 
4/8/2015
Samples

Discovery:

DX/Race AA Asian White Latino Other UNK Total
AD 2 20 153 0 3 4 182
FTD 0 8 110 1 5 4 128
PSP 0 1 12 0 2 7 16
Other 0 1 36 0 0 85 122
Control 0 27 182 5 4 6 224

 


Replication:

DX/Race

AA

Asian

White

Latino

Total

AD 138 13 68 21 240
Control 133 11 67 29 240

 

Phenotypes
DX/Race AA Asian White Latino Other UNK Total
AD 2 20 153 0 3 4 182
FTD 0 8 110 1 5 4 128
PSP 0 1 12 0 2 1 16
Other 0 1 36 0 0 85 122
Control 0 27 182 5 4 6 224

 

PI Information