The National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site

NIAGADS is the National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site. Supported by a U24 cooperative agreement between NIA and the University of Pennsylvania, NIAGADS is a national genetics repository to facilitate access by qualified investigators to genotypic data for the study of genetics of late-onset Alzheimer's disease.

Browse datasets

Available data

128

DATASETS

211,452

SAMPLES

DATA TYPES

Researchers

Submit a Data Acces Request, provide documents for a dataset submission, report any publications, or view NIAGADS documents and guidelines.

Recent news

Creating the Largest Joint-Called Whole Exome Sequencing (WES) Dataset for Alzheimer’s Disease (AD)

3/18/24

Over the last 20 years, the technology for DNA sequencing has rapidly evolved, making it possible to sequence individual whole genomes on a large scale. But when trying to find the underlying genetic causes of disease, every sequence donated matters. How can the sequences generated using older...

15 Genotyping Array Datasets From the Alzheimer's Disease Research Centers (ADRC) Now Available via DSS!

2/9/24

We are thrilled to announce the release of 15 much-anticipated genotyping array datasets from participants recruited from the Alzheimer's Disease Research Centers (ADRC)! These datasets, ADC1 through ADC15 , are now available on the NIAGADS Data Sharing Service (DSS). DNA was prepared by the...

Introducing hipFG: A high-throughput harmonization and integration pipeline for genomic annotations, QTLs, and chromatin interactions

1/5/24

A major challenge facing researchers today is the cleanup and harmonization of data for use in their work. As datasets get larger and the types of outputs continue to grow, this problem will continue to grow exponentially. Manually cleaning this data can be time consuming and prone to human error...

Alzheimer’s Disease Sequencing Project Update: Round 2 of the Harmonized Phenotypes and R4 36K Annotations Released

12/12/23

A new version of ng00067, the ADSP Umbrella Dataset is available on NIAGADS DSS . The ng00067.v11 release consists of: The round 2 harmonized phenotypes from the Phenotype Harmonization Consortium, which includes a subset of harmonized, ADSP-sequenced participant data from the following studies:...